A so-called "molecular chaperone", the protein Hsp70, carries out more functions in the maturation of proteins than previously thought. As the researchers have discovered, Hsp70 not only acts as a ...

Mitochondrial dysfunction, including decreased mitochondrial respiration and increased mitochondrial stress, is associated with many major human diseases and casual to many pathological defects.

Bonn, January 10, 2023 - Scientists led by Prof. Thomas Becker, Director of the Institute of Biochemistry and Molecular Biology at the University Hospital Bonn (UKB), have gained new insights into the ...

Using electron microscopy and high-speed atomic force microscopy, researchers show the internal molecular motor behind the gliding mechanism for Mycoplasma mobile to consist of two ATP synthase-like ...

In their high-resolution structure of Fo, the researchers found that the c-ring is plugged by two lipids, one from each side of the membrane. While the top (facing F1) lipid rotates along with the ...

The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP's central role, the structure of the enzyme generating ATP, F1Fo-ATP synthase, in mammals, including humans, has ...