For reference, a normal human X chromosome is also shown (X). For the X;22 (case 68) and X;14 (case 4) translocations involving band Xq13, the autosomal protion of the translocation chromosomes is ...

COLUMBUS, Ohio – Patients with acute myeloid leukemia (AML) who enter remission with abnormal chromosomes in bone marrow cells are twice as vulnerable to recurrence of their disease as are AML ...

The current study shows that cells with additional chromosomes have an altered mitochondrial structure and function. The reason: mitochondrial precursor proteins are sequestered in p62-positive ...

Chromosome 1 abnormalities (C1As) are among the most common recurrent chromosomal aberrations in multiple myeloma, and a post-hoc analysis of the E1A11 trial assessed the impact of C1As on newly ...

JA Rosenfeld is an employee of Signature Genomic Laboratories, a subsidiary of PerkinElmer, Inc. The authors have no other relevant affiliations or financial involvement with any organization or ...

Carfilzomib or bortezomib with lenalidomide, and dexamethasone (VRd) for initial therapy of newly diagnosed multiple myeloma (NDMM): Long-term follow-up of the ECOG-ACRIN ENDURANCE phase 3 trial. Real ...

DENVER -- Genetic testing and algorithms revealed that over 1% of more than 96,000 blastocyst-stage embryos had ploidy abnormalities, or atypical numbers of chromosomes. In total, ploidy abnormalities ...

Abnormal chromosomes can present challenges during cell division. A new study shines light on how this dysfunctional process may produce mutational patterns commonly found in cancer cells. Every time ...

Mother's Day is a happy day for millions, but for those who have experienced a miscarriage, the day can be devastating. As many as one in four recognized pregnancies result in miscarriage. Pregnancy ...

Cytogenetic technologists analyze chromosomes found in biological specimens such as amniotic fluids, bone marrow, and blood to aid in the study, diagnosis, or treatment of genetic diseases.