Transthyretin-mediated (ATTR) amyloidosis is a multisystem disease caused by the abnormal deposition of misfolded transthyretin protein as amyloid fibrils in various tissues. ATTR amyloidosis presents ...

Amyloid heart disease occurs when amyloid fibrils build up in the heart, making it more difficult for the heart to pump blood around the body. Eventually, this can lead to heart failure. People can ...

(BPT) – In 1982, Rosaline’s Aunt Polly passed away at age 58 from a rare disease called hereditary ATTR (hATTR) amyloidosis after enduring years of debilitating and progressive symptoms. Learning the ...

Cardiologist Dmitry Yaranov highlights amyloidosis as an underdiagnosed cause of heart failure, often mistaken for hypertension or aging. This conditi ...

AI algorithm has achieved remarkable accuracy in detecting cardiac amyloidosis, outperforming traditional diagnostic methods.

AL (immunoglobulin light chain) amyloidosis is a rare disease that often results in progressive organ dysfunction, organ failure and eventual death. Clonal plasma cells in the bone marrow secrete free ...

Patients were classified by phenotype and genotype and assessed by a range of validated scales in common use internationally. The cardiac phenotype was the most predominant one globally, affecting ...

Fact checked by Nick BlackmerFact checked by Nick Blackmer A recent study found people with carpal tunnel syndrome tend to develop cardiac amyloidosis, also known as “stiff heart syndrome,” about 10 ...

Please provide your email address to receive an email when new articles are posted on . Alnylam announced positive top-line results of its phase 3 trial of vutrisiran for the treatment of ATTR ...

With targeted treatment using both medical therapy for transthyretin-associated cardiac amyloidosis (ATTR-CA) and valve replacement for aortic stenosis (AS), patients with the dual pathology can fare ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...