Study identifies impaired ER-to-golgi ceramide transport as a key regulatory node underlying senescence-associated sphingolipid remodeling.

Scientists from Stanford University and the University of Texas MD Anderson Cancer Center have discovered a class of molecules that use endogenous proteins to modulate genetic pathways involved in ...

Zoie Magri does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...

Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the ...

We analyzed BIRC6 mRNA expression levels and copy number variations in three BC databases from The Cancer Genome Atlas comparing clinical and molecular attributes. Genomic analysis was performed using ...

A novel cell-free therapy restored hair growth, improved follicle structure, and showed no toxicity in preclinical models. Read more.

Researchers used a bioinformatics-plus-rat-model approach to investigate how palmatine may help treat T2DM-associated MASLD, ...

How did cells evolve a process to end their own lives? Recent research suggests that apoptosis, a form of programmed cell death, first arose billions of years ago in bacteria with a primitive ...