Atherosclerosis underlies most heart attacks and strokes and is now recognized as a chronic inflammatory disease rather than ...

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University ...

There is an emerging convergence between atherosclerotic cardiovascular disease and cancer, driven by shared risk factors and overlapping pathophysiologic mechanisms. Traditional factors, such as ...

Washington DC - The formation of new blood vessels around an atherosclerotic plaque appears to play a major role in plaque rupture, and antiangiogenic drugs may therefore represent a new therapeutic ...

Shown are the phases of rupture and healing of an atherosclerotic plaque. The cross-section of a plaque in Panel A shows a central core containing lipids and necrotic debris (yellow) and macrophage ...

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University ...

SEATTLE – University of Washington (UW) researchers have gathered evidence that dangerous plaques in blood vessels can rupture by overproducing protein-digesting enzymes. Plaques are fat-laden rough ...

Acute coronary events frequently result from atherosclerotic plaque rupture at apparently noncritical sites. Although pathologic examination shows that specific plaque characteristics correlate with ...

Atherosclerotic plaques are accumulations of fat, cholesterol and other substances in the arteries. Over time, these plaques can harden through a process called calcification. The degree of ...

Scientists have designed an immunotherapy that reduces plaque in the arteries of mice, presenting a possible new treatment strategy against heart disease. The antibody-based therapy could complement ...

A new antiplatelet drug with a completely novel mechanism of action may hold the promise of delivering the holy grail ― reducing cardiac events without increasing bleeding. That is the hope behind the ...