Leg pain and leg cramps aren't always an orthopedic issue: Both can be signs of peripheral artery disease, or PAD, a serious blood-flow issue with implications for the heart. In this expert alert, ...

Cholesterol buildup in your arteries can cause serious leg problems. Discover how peripheral artery disease affects millions ...

Imagine putting your socks on one morning and noticing your big toe, which has been painful for a few weeks, has started turning black. A trip to your doctor ends in being referred urgently to a ...

DEAR MAYO CLINIC: I'm 52 years old and enjoy long walks with my husband and our dog. I recently started to experience pain in my left calf during our walks. The pain goes away when I rest. Because I ...

Arteries can become blocked over many decades, before resulting in conditions that can become severe quickly. (Getty Images) Heart problems are very common in the UK, with around 7.6 million people ...

Cardiologists reveal the unexpected symptoms of clogged arteries and underlying heart disease that you should know about.

People in their 50s with severely narrowed leg arteries may face a high risk for major amputations despite having emergency surgery to restore blood flow to their legs, new research shows. The ...

DEAR MAYO CLINIC: I'm 52 years old and enjoy long walks with my husband and our dog. I recently started to experience pain in my left calf during our walks. The leg pain goes away when I rest. Because ...