“If we want to address BBB dysfunction, we have to have a good human BBB model,” said Ziyuan Guo, a neurobiologist and stem cell scientist at Cincinnati Children's Hospital Medical Center. “The whole ...

The central nerve system (CNS) plays a crucial central regulatory role in mammalian life, and the blood-brain barrier is the most selective physical barrier protecting the brain by strictly ...

New research reveals how a "leaky" blood-brain barrier connects sports-related head injuries to long-term brain disease like CTE.

For decades, scientists have struggled to understand exactly how years of taking hits to the head while playing sports can translate into severe memory loss and dementia later in life. Now, a study ...

Repeated head knocks cause long-term damage to the delicate blood-brain barrier, potentially driving chronic traumatic encephalopathy (CTE), a neurodegenerative condition that affects some former ...

The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been employed ...