The blood-brain barrier protects the central nervous system by tightly regulating what crosses between the two compartments. Neurons are vulnerable if the barrier suffers damage or weakens with age, ...

BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...

The brain's health depends on more than just its neurons. A complex network of blood vessels and immune cells acts as the brain's dedicated guardians—controlling what enters, cleaning up waste, and ...

Hypertension begins harming the brain surprisingly early, even before measurable blood pressure increases. Key cells related to blood vessels, signaling, and myelin maintenance begin aging prematurely ...

A study recently published in Nature has identified a key factor in the age-related breakdown of the blood-brain barrier (BBB) and has demonstrated that this damage may be reversible, potentially ...

The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been employed ...

Scientists have discovered that DMT, a natural compound found in plants and even the human brain, can dramatically reduce brain damage caused by stroke. The psychoactive molecule, long known for its ...