A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the ...
A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the ...
Sickle cell disease (SCD) altered CD8+ T-cell chromatin architecture, triggering ferroptosis and weakening antitumor immunity. Hydrogen sulfide (H2S) treatment restored chromatin interactions and ...
Immunity is orchestrated by two responses referred to as the innate and adaptive immune systems. Each system works to ...
CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...
Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...
Meet the Jekyll and Hyde of the immune system: activated CD8⁺ T cells. On June 24 in Nature Immunology, researchers led by Dorian McGavern at the National Institutes of Health introduce a granzyme ...
Immunotherapy has been one of the most transformative treatments for cancer patients in recent decades, shifting the emphasis ...
Published on March 23, 2026, in Volume 2, article number 18 of the journal Immunity & Inflammation , the review begins by systematically outlining ...
A University of Pennsylvania study has demonstrated that a dual-action lipid nanoparticle can reverse T-cell exhaustion and ...