Cell migration represents a fundamental physiological process that is intricately linked to cancer biology. The movement of cells is governed by dynamic interactions with the extracellular matrix (ECM ...

Solid tumors are heterogeneous with an immunosuppressive tumor microenvironment, but that is not slowing the search to treat the most difficult, recalcitrant cases ...

Alpha-enolase (ENO1) is a multifunctional enzyme primarily known for its role in glycolysis, where it catalyses the conversion of 2-phosphoglycerate to phosphoenolpyruvate. However, ENO1’s ...

The tumor microbiota—which includes bacteria, fungi, viruses, and other microorganisms present in tumor tissue—is now ...

Cells aren’t as passive as scientists once thought—they actively create internal currents to move proteins quickly and ...

Scientists in Canada have uncovered a surprising weakness in glioblastoma, one of the deadliest brain cancers. They found ...

A new CAR T-cell therapy attacks supportive cells in the tumor microenvironment that bear the surface protein, uPAR.

Using a variety of laboratory and animal models, the team found that cysteine fuels the production of the antioxidant ...

A common vitamin may be quietly helping cancer cells evade death. The body depends on vitamin B2, also called riboflavin, but ...

Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers like leukemia and ...

The Undergraduate Cancer Biology Society (UCBS) was started in 2022 with inaugural President Sarah Elimam. Now our third year as a UAB Registered Student Organization, UCBS is excited to continue its ...

This Research Topic focuses on cancers originating outside the central nervous system across the lifespan (including paediatric, adolescent, and adult ...