"The prize recognizes the confluence of two different approaches to learning about the molecular machinery regulating the cell cycle," says Ira Herskowitz, professor in the department of biochemistry ...

Arteriovenous malformations, a hallmark of hereditary hemorrhagic telangiectasia, may be driven by endothelial cell-cycle acceleration via CDK6, suggesting potential for repurposing CDK6 inhibitors.

A metabolic enzyme also binds and unwinds RNA to promote translation of cell cycle genes. This dual role links energy status to cell division, revealing a molecular switch that controls growth, and ...