Immune checkpoints are regulators of the immune system. The interaction between PD-L1 (red molecule) on the surface of a cancer cell (red) and the immune checkpoint PD-1 (blue molecule) on a T-cell ...

Checkpoint inhibitors act as a double-edged sword against cancer. Although they promote potent antitumor responses, they can also cause several adverse effects. This article joins a growing series on ...

Immune checkpoint inhibitors are well known as a form of cancer treatment. Researchers at UZH have now identified a new, important function of these inhibitors: promotion of tissue healing. This ...

Impact of protein-energy malnutrition on patients with breast cancer hospitalized for acute decompensated heart failure: Insight from the NIS database 2020. Effect of anti CTLA-4 and PD-1 monoclonal ...

ICIs, representing a revolutionary breakthrough in cancer immunotherapy, restore T-cell antitumor activity by targeting and blocking inhibitory immune molecules, thereby significantly extending the ...

The 2026 PSMA and Beyond conference featured an approaches to combination therapies session and presentation by Dr. Lawrence ...

Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body presumably curbs ...