A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides ...
Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...
A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...
From the moment an embryo starts to take shape, two-way communication is critical for making sure tissues and organs develop correctly. Two of the first physical structures to form in the embryo are ...
Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...
Precursor cells in the embryonic neural tube are organized in a specific striped pattern which depends on the signals they receive (left). Lehr and colleagues recreated this pattern in a cell culture ...
The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...