Post-translational modification by ubiquitin and ubiquitin-like proteins (ubls) regulates almost all aspects of cellular function. Although it is known that E1, E2 and E3 enzymes work together in a ...
Ubiquitin-like proteins (UBLs) such as NEDD8 are transferred to their targets by distinct, parallel, multienzyme cascades that involve the sequential action of E1, E2 and E3 enzymes. How do enzymes ...
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