Euan Ashley's lab explores the intricate interactions of gene variants. Tiny "typos," or genetic mutations, can sneak into segments of DNA. Many of these are harmless, but some can cause health ...

Imagine your doctor calls you to discuss the results of your genetic testing. They tell you your results indicate you are highly likely to develop Alzheimer's disease. But not to worry, because they ...

Epistatic interactions arise when the combined effect of two or more mutations on an organism’s fitness deviates from the sum of their individual effects. These interactions shape the topology of ...