Macrophages respond to Salmonella typhimurium infection via Ipaf, a NACHT–leucine-rich repeat family member that activates caspase-1 and secretion of interleukin 1β. However, the specific microbial ...
Many plants detect bacteria by the receptor FLS2 that binds the flagellin epitope flg22. A new pattern recognition receptor FLS3 in tomato detects flagellin from a second side; a further move in the ...
Summary The flagellin receptor of Arabidopsis, At-FLAGELLIN SENSING 2 (FLS2), has become a model for mechanistic and functional studies on plant immune receptors. Responses to flagellin or its active ...
In a study published in and featured on the cover of Gastroenterology, the official journal of the American Gastroenterological Association, researchers at the University of Alabama at Birmingham ...
In a new study, mice whose immune systems were trained against the microbial protein flagellin did not experience the usual detrimental effects of ingesting food additive emulsifiers, pointing to a ...
A new study reveals that motile Escherichia coli isolates demonstrated significant activation of NF-ºB signaling suggesting that flagellin plays a key role in up-regulating the host innate defenses ...
Flagella, which provide motility for pathogens like S. tyhimurium, contains flagellin, which is taken up by a splenic dendritic cell (purple). A specialized flaggelin sensor NAIP5 registers the ...
Can the brain sense bacteria in real time? A team at Duke University has found that specialized gut cells detect a microbial protein and send a rapid signal to the brain that suppresses appetite. The ...
A new study reveals how your gut bacteria can directly tell your brain when to stop eating, opening fresh avenues for appetite and metabolic research. Study: A gut sense for a microbial pattern ...
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