Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled “A combination of differential expression and network connectivity analyses ...

Humans have selectively bred animals and crops since the beginning of agriculture, but advances in biotechnology have provided genetic tools to select specific traits. First applied to animals in the ...

A major medical milestone took place in May 2025, when doctors at the Children’s Hospital of Philadelphia used CRISPR-based gene editing to treat a child with a rare genetic disorder. Unlike earlier ...

Daniel Mills does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...

A committee-supported project or activity that has been completed and for which output dissemination has begun. Its committee has been disbanded and closeout procedures are underway. An ad hoc ...