Please provide your email address to receive an email when new articles are posted on . An analysis of registry data from the United Network for Organ Sharing suggests that human leukocyte antigen ...

Only 30% of patients in need of allo-HSCT will have a suitable human leukocyte antigen (HLA)-matched family member, and in the remainder an unrelated donor (UD) may be sought. 12 Although studies on ...

Please provide your email address to receive an email when new articles are posted on . For years, hematopoietic stem cell transplantation physicians have viewed a matched unrelated donor as the gold ...

CAR T-cell therapy successfully cleared anti-HLA antibodies to enable kidney transplantation in three highly sensitized ...

Background Owing to contradictory results, HLA matching in penetrating keratoplasty still is equivocal. Different surgical techniques in multicentre studies, missing risk differentiation in high-risk ...

HLA testing has been a staple in transplantation since the recognition that antibodies, directed against lymphocytes, were associated with allograft failure. This seminal finding led to the discovery ...

In this JCO Article Insights episode, Alexandra Rojek provides a summary on "Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use ...

"Histo" means "tissue." Histocompatibility is defined as a measure of how well 2 tissues "get along with one another" when they find themselves in a confined space. The major physiologic barrier in ...

“Since the discovery of transplantation as a life-saving therapy for blood malignancies by Dr. E Donnall Thomas, there have been major advances that have significantly lowered the side effects and ...

Researchers at the University of Pittsburgh have identified a new way of predicting whether a kidney donor and recipient are a good match for transplantation. The findings, published today in Science ...

BLEAT is designed to work in three parts. Firstly, it is required to input the transplant recipient’s HLA-B typing information into the software, alongside HLA-B typing information for any potential ...

This podcast comments on a large registry study evaluating the effect of ultra-high-resolution HLA typing on outcomes of unrelated donor transplantation. For patients who are potential candidates for ...