Antibody-mediated rejection (ABMR) remains the leading immunological cause of kidney allograft loss, yet its humoral origins are incompletely understood.

Marginal zone B (MZB) cells play pivotal roles in the innate immune system by linking innate and adaptive immunity through their capacity for antigen presentation and lymphocyte activation 1,2.

Herpesviruses are highly species-specific, having co-evolved with their respective hosts over millennia. This evolutionary relationship has led to the development of highly specialized immune evasion ...