Different DNA Structures Nucleate the Folding of Proteins to form specific complexes that modulate the readout of ...

Molecular dynamics simulations yield thermodynamic and time-dependent behavior, elucidating the role of intrinsically ...

Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, "droplets" of concentrated proteins, DNA ...

In synthetic and structural biology, advances in artificial intelligence have led to an explosion of designing new proteins with specific functions, from antibodies to blood clotting agents, by using ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular ...

Researchers at Harvard and Northwestern have developed a machine learning method that can design intrinsically disordered proteins with custom properties, addressing nearly 30% of all human proteins ...

Deep learning tools for protein design can also be used to create molecules that bind to them. Certain peptides, such as intrinsically disordered proteins (IDPs), are challenging to target due to ...

Protein dynamics and intrinsic disorder represent a paradigm shift in our understanding of protein structure and function. Rather than depending solely on a single stable three‐dimensional structure, ...

A milestone in biology has been achieved thanks to artificial intelligence (AI) machine learning and applied physics. A new peer-reviewed study by researchers affiliated with Harvard John A. Paulson ...

(MEMPHIS, Tenn. – December 3, 2025) Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, ...