Not many drugs are as widely used yet poorly understood as anesthetics. “We’ve used them for over a century, but nobody understands how they work,” says Alex Proekt, an anesthesiologist and ...

Desflurane may be a safer anesthetic option for patients with Alzheimer’s disease, due to the associated of the inhaled anesthetic isoflurane with the disease, according to a News-Medical report. In a ...

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Inhaled isoflurane sedation was on par with IV midazolam for children age 3 to 17 years in the ICU on mechanical ventilation in a randomized trial. Isoflurane also reduced time to extubation and ...

A recent study on the effects of commonly used anesthetic and sedative drugs on cerebrospinal fluid flow and volume has uncovered significant findings regarding their impact on the brain's vital ...

Isoflurane has been characterized as a distressing agent for rodents, causing both physiologic and behavioral effects. Using a "darkened home cage" has been recommended during CO2 administration for ...