A 2017 study looked at a lidocaine-prilocaine spray. (Prilocaine is another desensitizing agent.) The study found that the product was fast-acting, working within five minutes of men spraying it ...

Lidocaine 2.5%, prilocaine 2.5%. Topical anesthetic on normal intact skin for local analgesia or on genital mucous membranes for superficial minor surgery and as pretreatment for infiltration ...

Dinsmore and colleagues investigated the efficacy and safety of topical eutectic lidocaine–prilocaine mixture for premature ejaculation (TEMPE), applied to the glans penis via a metered-dose ...

In a 12 week, double-blind RCT, a metered-dose aerosol spray containing lidocaine and prilocaine (PSD502) showed a 6.3-fold increase in intravaginal ejaculatory latency times, improved all patient ...

Despite the frequent use of lidocaine as an anesthetic and its occasional use as a therapeutic agent, reports of ACD from lidocaine and delayed hypersensitivity reactions to it are even more limited.