Pancreatic cancer may evade the immune system not by accident but by actively switching off internal danger signals through ...
When compared to tumors from European American men with mCRPC, African American men with mCRPC demonstrated a higher expression of MYC pathway genes and lower expression of IFN-γ, IL-6/JAK/STAT3 and ...
CARD14 directly binds and regulates MYC, a protein involved in controlling cell growth that can contribute to cancer when it malfunctions. A study published in Cell Reports shows that the proper ...
This model illustrates how SETD1B promotes the expansion of H3K4me3 epigenetic marks and upregulates MYC expression, driving cytokine-independent cell growth in FLT3-mutated AML. Acute myeloid ...
The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system. This finding from a new study offers a promising way to improve existing cancer therapies ...
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MYC gene's dual role in cancer growth and immune suppression
The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.
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