The body's endogenous opioid system has three classes of opioid receptors: mu, delta, and kappa. Previous research showed that mice lacking the mu opioid receptor do not drink alcohol. A new study ...

Alcohol-use disorders have a significant genetic component to their development. New findings show that heavy drinkers with the G allele of the A118G polymorphism of the mu-opioid receptor gene have ...

Fentanyl, a mu-opioid receptor agonist, is one of the most commonly used analgesics in hospitals, and may induce long-lasting behavioral and somatosensory impairment in rodents. However, whether the ...

Researchers have observed that the length of daylight hours impacts opioid receptor levels in brown fat. When daylight hours shorten, the receptor activity levels elevate. A similar phenomenon also ...

Kappa delta mu sounds like a college fraternity. And if you associate college with sometimes fatal outbursts of binge drinking, the Greek letters might be a fitting label. For neuroscientists, though, ...

Having a pill that alleviates chronic pain without adverse side effects or the risk of addiction remains an unmet pharmaceutical need for millions of people currently using traditional opioid drugs.

SB 299 sets a national example by banning dangerous concentrated synthetic 7-OH opioids while protecting access to safe, ...

Researchers from the Turku PET Centre, Finland, have observed that the length of daylight hours impacts opioid receptor levels in brown fat. When daylight hours shorten, the receptor activity levels ...

Brandy Schillace’s review of “Candace Pert” by Pamela Rykman (Bookshelf, Nov. 15) contains a questionable conclusion: the discovery of the mu opioid receptor in 1972 “helped launch the opioid crisis” ...

PN6047 is a first-in-class small molecule that selectively activates the delta opioid receptor (DOR), avoiding interaction with the mu opioid receptor that is the basis of the addiction and other ...