Experts from around the NFL make their picks for a Week 8 game between the New York Giants and Philadelphia Eagles.

The Tennessee Titans (1-6) are back on the road this Sunday when they face the Indianapolis Colts (6-1) at Lucas Oil Stadium in Indianapolis, Indiana, at 3:25 p.m. CDT. Opening the week, the Titans were listed as 14-point underdogs, and as of this writing, that is where the spread currently sits.

The Rams lead the all-time series 5-1, including wins in each of the last three meetings. The Rams are 3-point favorite in the latest Jaguars vs. Rams odds, while the over/under for total points scored is 44.

NFL Week 8 kicks off when the Minnesota Vikings and Los Angeles Chargers meet on Thursday Night Football tonight. TNF start time, TV schedule and how to watch

Mac Jones continues under center for the 49ers (5-2) when they travel to Houston for a Sunday afternoon tilt against the Texans (2-4). Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the Rams.

The Los Angeles Chargers are hosting the Minnesota Vikings on Thursday, Oct. 23 to open Week 8 of the NFL season.

Here’s how the Texans and 49ers stack up statistically ahead of Sunday's matchup at NRG Stadium in Week 8 of the NFL regular season.