Nasdaq

Bruker Supports International Covid19-NMR Consortium for Structure-Function and Inhibitor Binding Investigations of SARS-CoV-2 RNA and Proteins

The fight against the global COVID-19 pandemic is one of the greatest challenges currently facing mankind. The international Covid19-NMR consortium aims to determine the dynamics, function and ...
Nature

NMR characterization of RNA binding property of the DEAD-box RNA helicase DDX3X and its implications for helicase activity

The DEAD-box RNA helicase (DDX) plays a central role in many aspects of RNA metabolism by remodeling the defined structure of RNA molecules. While a number of structural studies have revealed the ...
Nature

Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex

For decades, the weight of atomic-resolution structure elucidation, a requirement for understanding biomolecular mechanisms in detail, has been almost exclusively borne by X-ray crystallography, as ...
Phys.org

NMR confirms molecular switches retain function in 2-D-array

Researchers led by Jiří Kaleta of IOCB Prague have synthesized regular 2-D assemblies of isotopically labelled molecular switches and measured the properties of their isomerization, revealing that ...
News Medical

New NMR technique reveals atomic-scale motion in catalytic enzyme function

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex ...
ascopubs.org

Identification and functional characterization of long noncoding RNA NMR as biomarker for metastasis and prognosis in esophageal squamous cell carcinoma.

ERBB pathway alterations in advanced gastric signet-ring cell carcinoma (SRCC) and the implications for targeted therapy. Prognostic factors associated with survival and recurrence in resectable ...