Neurofibromatosis type 1 (NF1) is a prevalent genetic disorder caused by germline mutations in the NF1 gene, leading to dysregulation of RAS signalling and predisposing affected individuals to diverse ...
Neurofibromatosis type 1 (NF1) is a rare genetic condition that affects how certain nerve cells grow and develop. Children with NF1 can have small growths on or under the skin called neurofibromas.
We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Mirdametinib is an investigational mitogen-activated ...
Almost half of adults and children with neurofibromatosis type 1 (NF1) responded to the investigational MEK inhibitor mirdametinib, a large multicenter study of the rare condition showed. Overall, 53 ...
Researchers identify bone-forming cells as the driver of scoliosis caused by a genetic disorder, which can be prevented ...
CHICAGO -- Selumetinib (Koselugo) significantly improved response rates in adults with neurofibromatosis type 1 (NF1) and symptomatic, inoperable plexiform neurofibromas, the phase III KOMET trial ...
We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Koselugo’s approval was based on data from the phase 3 ...
Most NF1-PNs cannot be fully removed with surgery or other treatments. Therefore, it’s important to take steps to manage the condition and reach out to others for support as you enter adulthood. Many ...
Dermatology is entering a "biological revolution," with engineered tissues and bio-machines offering new therapeutic ...
A team of researchers from the Germans Trias i Pujol Research Institute (IGTP) and Institut Català d'Oncologia (ICO) has studied alterations in the KRAS gene in colorectal cancer by combining genomic ...
The Global Plexiform Neurofibroma Market centers on the treatment of plexiform neurofibromas, benign nerve sheath tumors linked to Neurofibromatosis Type 1 (NF1). These tumors cause significant ...