Congenital myasthenic syndromes (CMSs) are a heterogeneous group of disorders that affect the safety margin of neuromuscular transmission — the depolarization that is required for propagation of the ...
It is important to understand the principles of normal neuromuscular transmission when using neuromuscular blocking agents. The neuromuscular junction consists of the motor-nerve terminus, the ...
Findings published in The American Journal of Pathology identify GLUD1 enzyme as a potential therapeutic target for muscle restoration through metabolic reprogramming, addressing clinically unmet need ...