Bone homeostasis is regulated by communication between bone-forming mature osteoblasts (mOB) and bone-resorptive mature osteoclasts (mOC). However, the interaction between them in vivo remains unclear ...

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...

Researchers led by Kanazawa University show that messages sent by osteoblasts via extracellular vesicles trigger the formation of mature osteoclasts during fracture healing Kanazawa, Japan - In a ...

Background. A 55-year-old woman with a 5-year history of osteoporosis treated for 4 years with an oral aminobisphosphonate presented with a recent vertebral fracture. A bone biopsy specimen revealed ...

Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones. But the intracellular mechanisms ...

A new discovery about osteoporosis suggests a potential treatment target for that brittle-bone disease and for bone loss from rheumatoid arthritis. The findings from University of Virginia School of ...

The skeleton undergoes continuous remodeling throughout life in response to diverse environmental stimuli. Osteoclasts, which are specialized cells on the bone surface, break down old bone tissue (in ...

Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones. But the intracellular mechanisms ...

Researchers at the Garvan Institute of Medical Research have discovered a new type of bone cell that may yield novel therapeutic targets and strategies for osteoporosis and other skeletal diseases.

This is a rare peek at how cartilage transforms into bone. In this image, you can see cartilage (in purple and white), blood vessels and cells (in yellow), and other specialized cells that create ...