DNA damage, caused by radiation and a variety of chemical agents, can lead to mutations, genomic instability, cancer and cell death. Genetic studies in the yeast Saccharomyces cerevisiae have revealed ...

Protein ubiquitylation is now recognized as a major post-translational modification in eukaryotes. Either a single ubiquitin moiety or a ubiquitin chain can be conjugated to the target protein at a ...

A recent study published in the Cell Chemical Biology Journal described a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) that selectively kills cancer cells. PCNA is a conserved ...

Innovative dual system for selective eradication of cancer cells using exosomes carrying natural bacterial toxin-antitoxin (TA). This is an ASCO Meeting Abstract from the 2019 ASCO Annual Meeting I.

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, today published a new study explaining how they took a protein once thought to be too ...

This article may contain links from our affiliate and advertising partners. We may receive payments when you click on links, buy through them or share this content. Scientists at City of Hope, one of ...