Role of histone deacetylase expression on regulating cancer stem cells in intrahepatic cholangiocarcinoma. Phase I/II study of PCI-27483, a coagulation factor VIIa (FVIIa) inhibitor in patients with ...
Diminished platelet autophagy potentially contributes to thrombocytopenia in cirrhotic patients. H 2 S modulates platelet autophagy and functions possibly via the PDGFR-α/PI3K/Akt/mTOR signaling ...
This study is led by Dr. Jianxin Jiang (Institute of Department of Trauma Medical Center, Daping Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, Army Medical University). The team ...
Sunitinib (SU)-related hypertension in a randomized placebo (P)-controlled trial of GIST patients (pts). Background: CS is a rare and heterogeneous disease in which, after failure of surgery and ...
A Voronoi Bio Inc. and Voronoi Inc. patent describes platelet-derived growth factor receptor (PDGFR), mast/stem cell growth factor receptor kit (KIT; c-Kit; CD117) and their mutant inhibitors reported ...
Actelion Pharmaceuticals Ltd. has disclosed platelet-derived growth factor receptor beta (PDGFR-β) inhibitors reported to be useful for the treatment of pulmonary arterial hypertension.
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