Drexel University scientists have discovered an unusual mechanism for how two new antimalarial drugs operate: They give the parasite’s skin a boost in cholesterol, making it unable to traverse the ...

Comprehensive genetic mapping of Plasmodium knowlesi, a zoonotic parasite that causes malaria, has revealed the genes required for malaria infection of the blood, and those driving drug resistance. By ...

A team of researchers has found that the Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune ...

Malaria is a devastating disease caused by the Plasmodium parasite. After an infected mosquitos' bite, the parasites travel to the liver and infect liver cells. This phase of the infection is ...

A new study led by Maria Manuel Mota, group leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), now shows that malaria parasites secrete the protein EXP2 that is required for ...

For the first time the developmental stages of the deadliest human malaria parasite, Plasmodium falciparum, have been mapped in high resolution, allowing scientists to better understand this ...

Malaria, a disease caused mainly by the parasites Plasmodium falciparum and Plasmodium vivax, is associated with over 400,000 deaths each year. Previously, the spleen was assumed to mostly play a role ...

Researchers have chanced upon a bacteria naturally present in the gut of mosquitoes that inhibits the growth of a parasite that causes the deadliest form of malaria. Unlikely to produce resistance, ...

Living on a diet of blood requires some specific adaptations, such as a way to keep the food source flowing. To prevent their meal from turning into an indigestible clot, mosquitoes evolved very ...