The human heart must constantly adapt to changing demands—a task that requires tightly coordinated molecular shuffling in ...

Cardiac disease While our current research has shed light on the evolution of the human heart, our work analyzing the hearts of endangered great apes continues. Sadly, cardiac disease is the leading ...

Many promising therapies fail because preclinical models do not fully capture the complexity of the human heart. A new review ...

Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists -- so far. A new multi-chamber ...

Researchers have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development. The ...