RNA molecules exhibit an astonishing diversity in structure, which is integral to their myriad cellular functions ranging from gene regulation to catalysis. Advances in experimental techniques and ...

They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes ...

Studying a trio of non-coding RNA molecules produced abundantly in bacterial cells, a SLAC/Stanford-led research team discovered extravagant, multistrand complexes made entirely of RNA—structures they ...

Despite being made from a relatively simple set of building blocks, ribonucleic acid (RNA) has a broad array of complex responsibilities. From providing structure to carrying the instructions for ...

In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

Next, they considered size, but found that alone cannot explain the enrichment, so the team turned to RNA structure—and started to piece the puzzle together. "With advances in structural biology of ...

Torino is a computational workflow that uses biobank-scale RNA-seq data to decode transcript structures and expression levels from read coverage alone.

Researchers discovered that a circular RNA is crucial for synapse development and plasticity in the mouse visual system.

Wiring up the brain's trillions of circuit connections is an enormous job performed by a huge crew of molecules. Among the less understood members are circular RNAs, transcripts from DNA that assume a ...

Recently, demands in RNA manufacturing for long-chain RNAs exceeding 100 nucleotides, such as single guide RNA (sgRNA) for genome editing, have been increasing. Generally, these types of RNA are ...

The field of RNA structure prediction and modeling has undergone substantial transformation in recent years, reflecting a confluence of innovative computational strategies and expanding experimental ...