San Francisco 49ers quarterback Brock Purdy is expected to miss the team's Week 8 matchup against the Houston Texans amid his recovery from turf toe, NFL Network's Ian Rapoport reported Thursday.

San Francisco 49ers running back Christian McCaffrey (23) runs against Atlanta Falcons linebacker Kaden Elliss (55) in the second half of an NFL football game, Sunday, Oct. 19, 2025, in Santa Clara, Calif. Credit: AP/Kelley L Cox

The 49ers’ defense is coached by former Jets head coach Robert Saleh, who is known throughout NFL circles as one of the brightest defensive minds in the game. Saleh, a native of Michigan, has been linked to college football head coaching jobs recently during an NFL season that is still in full swing.

Houston has a short week ahead of them after a tough loss on the west coast. They face the San Francisco 49ers, who are coming off a strong victor against the Atlanta Falcons. FanDuel has released their initial odds and they have several interesting options for fans who are interested in placing bets on the Texans game.

Find single game tickets to the Houston Texans vs. San Francisco 49ers NFL Week 8 matchup on Sunday, October 26, 2025 at NRG Stadium.

Quarterback Brock Purdy remains limited by a toe injury and could miss his fourth straight game for the San Francisco 49ers.

Head coach Kyle Shanahan revealed the changes he made that appear to have paid off for the better. The 49ers’ 6-11 2024 campaign was arguably one of the worst of the Shanahan era, with the Super Bowl defeat hangover playing a major role.

The Atlanta Falcons traveled to Santa Clara, California to take on the San Francisco 49ers on "Sunday Night Football." Here's what happened in Week 7.

Christian McCaffrey has his first 100-yard rushing game since 2023, helping the San Francisco 49ers beat the Atlanta Falcons 20-10 on Sunday night.