You wouldn't necessarily think it from the damage he sustains over the course of "Novocaine," but Nathan Caine ranks among the most risk-averse action heroes the genre has ever seen. That's because the junior manager of a San Diego bank has a rare disorder known as congenital insensitivity to pain with anhidrosis (or CIPA).

Kuato couldn't possibly have known that Quaid would one day star in an ultraviolent chase movie rom-com where he elicits stunned and screaming reactions from the audience as he pu