Cholelithiasis is the formation of gallstones in the gall bladder, composed of cholesterol, pigments, or mixed salts. Risk factors include obesity, drugs, infections, and bile stasis. It may be ...

Calculous cholecystitis is a gallbladder inflammation that occurs due to the presence of gallstones (cholelithiasis). These gallstones can block the cystic duct, the channel through which bile flows ...

Biliary pancreatitis occurs when gallstones develop in your gallbladder and block the duct that leads through your pancreas to your small intestines. Gallstones develop from hardened pieces of ...

A new study published in the journal Gut has shed light on the complex relationship between serum lipids, lipid-modifying targets, and cholelithiasis, a common condition characterized by the formation ...

DEAR DR. ROACH: What advice do you have for the treatment of gallstones? -- N.W. ANSWER: Gallstones are common (6% of men and 9% of women will get one over a lifetime) and are mostly composed of bile ...

Gut microbiota produce trimethylamine, which enters the liver via the portal circulation and is primarily oxidized by FMO3 to produce TMAO. TMAO upregulates hepatic PCSK9 gene expression while ...

Cholesterol synthesis and gallstone formation are promoted by trimethylamine-N-oxide (TMAO), a derivative of trimethylamine, which is a metabolite of gut microbiota. However, the underlying mechanisms ...

Unless you’ve had gallstones, you’ve probably never given a second thought to your gallbladder. However, gallbladder cancer, when found at an advanced stage, is quite deadly. Fortunately, it’s ...