Zebrafish xenograft models are increasingly recognized for predicting patient responses to cancer therapeutics, suggesting their potential as clinical diagnostic tools. However, precise microinjection ...

Zebrafish is an established valuable model for understanding the complex in vivo behavior of systemic nanocarrier strategies, their safety profile, and the array of possible compositions. To date, we ...

Can a small fish help identify possible treatments for an ultra-rare inherited disease found in an Alabama boy? The genetic disease is XMEA, which progressively weakens the muscles and can affect the ...

Scientists at the National Eye Institute (NEI) have developed a zebrafish model of NEDBEH—a rare genetic disorder that can cause coloboma, where parts of the eye are missing due to developmental ...

Senescence (the process of growing old) drives the onset and severity of multiple aging-associated diseases and frailty. As a result, there has been an increased interest in mechanistic studies and ...

In recent years, many research studies have been conducted to assess the therapeutic use of nanomedicines. This is due to their enhanced stability and solubility, ability to overcome transport ...

Researchers explore drug-seeking behavior with a zebrafish animal model. As the opioid crisis escalates, the science behind addiction remains poorly understood. To address this need, researchers at ...

Preclinical drug evaluation, especially for cardiotoxicity, is a critical stage in the drug development process. Traditional methods, often relying on in vitro assays or manual manipulation of animal ...

Researchers use zebrafish models to discover that the RLS risk gene MEIS1 regulates Purkinje cell survival and motor control.