Increased volume of the choroid plexus, which produces and secretes cerebrospinal fluid (CSF), was tied to cognitive impairment and Alzheimer's disease, a retrospective study showed. Among 532 adults ...

The image of the “blood-brain barrier” as a static wall that shields the brain from the rest of the body is crumbling. A group of scientists argue, in a review published in Fluids and Barriers of the ...

The blood-brain barrier prevents xenobiotics from entering the central nervous system. Growing evidence indicates that neurotoxins, such as tributyltin, manganese and nanoparticles, may disrupt the ...

Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...

In the “omics” era, where bigger is better, the Global Neurodegeneration Proteomics Consortium is making a splash. To date, this two-year-old initiative led by Gates Ventures and Johnson & Johnson has ...

Enough pints of beer can have you falling off your bar stool or loudly reciting lyrics to early 2000s jams to total strangers, because alcohol can get past one of the strongest defenses in the body.

The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been employed ...

Denali Therapeutics is poised to revolutionize the industry with its proprietary Transport Vehicle (TV) technology, designed to effectively cross the blood-brain barrier. The company's robust and ...