While it wasn't an easy span of days for every Colorado Buffaloes draft prospect, it turned out to be one of the most successful NFL drafts for the program in a long time. After Travis Hunter was selected No.

Shedeur Sanders was the big story of the 2025 NFL draft, as the former Colorado quarterback went from a first-round projection to a fifth-round pick over three stunning days. He was finally taken off the board by the Cleveland Browns with the 144th pick,

Travis Hunter was the headliner at No. 2 overall to the Jacksonville Jaguars, while LaJohntay Wester (No. 203 overall to the Baltimore Ravens) and Jimmy Horn Jr. (No. 208 overall to the Carolina Panthers) went in the sixth round.