(a) General diagram of the miRNA biogenesis pathway. (b) The major routes of cadmium exposure and its toxic impacts. AGO, Argonaute; Cd, cadmium; Exp5, Exportin 5; miRNA, microRNA; Ran/GTP, ...

To discover and thoroughly demonstrate the newly identified noncanonical cleavage mechanism, the Hong Kong University of Science and Technology (HKUST) research team, led by Prof. Tuan Anh Nguyen, ...

MAC5 is a component of the conservedMOS4-associated complex. It plays critical roles in development and immunity. Here we report that MAC5 is required for microRNA (miRNA) biogenesis. MAC5 interacts ...

MicroRNAs can make plants more capable of withstanding drought, salinity, pathogens and more. However, in a recent study scientists showed just how much we didn't know about the intricate processes ...

4-Hydroxynonenal (4-HNE) is a major byproduct of lipid peroxidation, a process exacerbated by mitochondrial dysfunction and oxidative stress. Accumulation of 4-HNE protein adducts has been reported in ...