Eight years on from the formation of the Human Cell Atlas (HCA) consortium, which set out with the hugely ambitious task of mapping the entire human body – around 37.2 trillion cells – scientists ...

Welcome to Lab Dish, a First Opinion column on regenerative medicine from Paul Knoepfler. Twenty years ago, the use of human embryonic stem cells in research was among the most fiercely debated topics ...

Thanks to increasingly efficient and affordable gene sequencing technologies, we can now chart our genetic blueprint in unprecedented detail. But what does each gene do? Of the roughly 20,000 genes ...

A team of UK-based researchers is going where no scientist has dared to go—writing artificial human DNA from scratch. They’re hoping the project will answer fundamental questions about the human ...

The first phase of the U.K. synthetic human genome project has successfully completed, realizing key steps in chromosome synthesis. The work has demonstrated a multistep method for transfecting mouse ...

An unprecedented international effort to decode how cells manage the transport of chemical substances has culminated in four studies published in Molecular Systems Biology. Led by Giulio Superti-Furga ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought. The ...