An international research team from Bielefeld University and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP ...

Draupnir’s novel SORTAC platform expands reach of targeted protein degradation to extracellular proteins, demonstrating in vitro and in vivo efficacy against difficult-to-drug targetsStudy further ...

Macrophages, the immune system’s front-line scavenger cells, do more than simply digest dead cells. A new study published in ...

The mechanism by which cells detect leaky lysosomes has been revealed, laying the groundwork for new treatments for diseases where lysosomal damage plays a central role. When the cell’s recycling ...

Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...

Researchers have identified a crucial ion channel, TMEM175, that acts like an overflow valve in the cell’s recycling system.

Transmission electron microscopic image of an isolate from the first U.S. case of COVID-19, formerly known as 2019-nCoV. The spherical viral particles, colorized blue, contain cross-section through ...

Scientists have uncovered a hidden reason why cancer treatments don’t work equally well for everyone. Certain drugs can ...

Of the 20,000+ human genes, none has greater influence on late-onset Alzheimer’s disease than APOE. But why do certain variants of this lipid transporter protect the brain, while others endanger it? A ...

Hutchinson-Gilford progeria syndrome (HGPS) is a rare progeroid disorder, featured with premature skin wrinkling, lack of skin elasticity, absence of subcutaneous fat, alopecia, atherosclerosis and ...