The frame-shift mutation (c.1691_1693delinsG) of SCNN1B gene was identified by whole-exome sequencing and Sanger sequencing in a family with hypertension.

PRISM’s genome is engineered to include a repeat sequence with a frameshift mutation. Once inside a cell, the host’s DNA replication machinery reverts the frameshift while converting the single-strand ...

Discovery of a Recurrent Frameshift Ashkenazi Jewish Founder Mutation (F722fs) in the PARP Inhibitor–sensitive MMS22L Gene Associated with Higher Risk of Prostate Cancer.

Cornelia de Lange syndrome (CdLS) is a developmental genetic disorder. The characteristics of CdLS remain unexplored in the Chinese population. Now, a group of researchers from the National Center for ...