GitHub

Rmarkdown / compiled html files for human reprogramming dataset analysis

hrpi_1main.Rmd: Rmarkdown for analysing integrated sn/scRNA-seq of human reprogramming intermediates (click here for compiled html) hrpi_2geneSig.Rmd: Rmarkdown for identifying gene signatures from ...
Frontiers

Spatial transcriptome and single-cell sequencing reveal the role of nucleotide metabolism in breast cancer progression and tumor microenvironment

The final, formatted version of the article will be published soon. Abstract Background: The complexities of nucleotide metabolism in breast cancer (BC) cells are not yet fully understood. A deeper ...
GitHub

A scalable method to infer fate specific gene regulatory network from single cell gene expression data

conda create --name NetID -c conda-forge -c bioconda r-seurat=4* python=3.10 r-essentials r-base=4.2.0 conda activate NetID # if it encounter the error, run 'source activate' ahead of this code To ...
Frontiers

Novel pan-cancer T cell exhaustion signature forecasts immunotherapy response and unveils BCAP31 in macrophages as a therapeutic target in neuroblastoma

Introduction: Gaining insights into the molecular features associated with T cell exhaustion (TEX) can offer fresh perspectives on predicting treatment responses, and we aim to investigate TEX-related ...