In a six-year-old boy with congenital sex-linked hypogammaglobulinemia, Coombs-test positive autoimmune hemolytic anemia developed despite profound deficiencies of immunoglobulins. Direct and indirect ...
ACQUIRED hemolytic anemia is commonly associated with a positive Coombs test; when of the "gamma type," this test indicates the presence of an immunoglobulin attached to the affected red cells. The ...