The cell's endoplasmic reticulum (ER) plays a central role in protein synthesis, folding, and calcium (Ca²⁺) storage. When ...

Hyderabad have identified a mammalian protein, Cnpy1 (Canopy1), that is essential for the survival and function of ...

What is the Cnpy1 protein? New research reveals how the Canopy1 protein allows vomeronasal neurons to survive high ER-stress.

Multiple myeloma is an incurable blood cancer with complex treatment needs. AI is increasingly used to accelerate drug ...

Gain Therapeutics, Inc. (Nasdaq: GANX) (“Gain”, or the “Company”), a clinical-stage biotechnology company leading the discovery and development of the next generation of allosteric small molecule ...

Ceramide buildup due to faulty transport triggers stress responses that lock cells into senescence, revealing a potential ...

Study identifies impaired ER-to-golgi ceramide transport as a key regulatory node underlying senescence-associated sphingolipid remodeling.

When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as replicative senescence, cells remain alive but no longer proliferate.