The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at the base of crypts.

Aardvark Therapeutics, Inc. (Aardvark) (Nasdaq: AARD), a clinical-stage biopharmaceutical company focused on developing novel, small-molecule therapeutics to activate innate homeostatic pathways for ...

The recent discovery of glycoRNAs on the cell surface upended the world of cell biology. These glycoRNAs were found to form highly organized clusters with cell surface RNA binding proteins (csRBPs), ...

Researchers have identified a biological mechanism that helps explain why some lung and ovarian cancers become resistant to ...

Primary immunodeficiencies are genetic disorders that impact on the immune system due to defective function of a variety of genes. Among those molecules are ...

A team of researchers at RPI, in collaboration with the University of South Florida, University of North Carolina, and The Neural Stem Cell Institute, have made a discovery that opens the door to new ...

Krabbe disease, also called globoid-cell leukodystrophy, is caused by a deficiency of the lysosomal enzyme β-galactosylceramidase (GALC), resulting from pathogenic variants in both copies of the GALC ...

Precise coordination of cell growth and cell-cycle progression is essential for maintaining tissue integrity and organismal health. When these regulatory ...