Diagnosis Thrombotic microangiopathic hemolytic anemia with a possible underlying diagnosis of malignant hypertension, antiphospholipid antibody syndrome, catastrophic antiphospholipid antibody ...

Schistocytes on peripheral blood smear are an important diagnostic feature of these disorders.

Atypical hemolytic uremic syndrome is a rare condition caused by the uncontrolled activation of complement, and subsequently leads to complement-mediated thrombotic microangiopathy. The condition ...

A peripheral-blood smear revealed spherocytes and nucleated red cells, plus polychromasia. At the nadir of his condition, the patient was treated for symptomatic anemia with 2 units of packed red ...

Spherocytes can occur in neonatal immune hemolytic anemia, particularly ABO hemolytic disease, in sepsis, microangiopathic hemolytic anemias and hemoglobin H disease.

PAROXYSMAL nocturnal hemoglobinuria is a rarely recognized cause of hemolytic anemia. Although the exact etiology remains obscure, the erythrocytes develop a defect that sensitizes them to increase ...