Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted ...

Cancer cells turbocharge themselves by stealing the energy-producing units from neurons in tumours, scientists report today in Nature 1. This act of thievery seems to give cancer cells a boost to ...

T cells transformed in vivo to target B cells could widen the scope of diseases treated by chimeric antigen receptor T-cell therapy.

The cure for diabetes is a life free from daily insulin injections. Based on that criterion, ten out of 12 people (83%) in a new clinical trial were cured of their diabetes one year after ...

Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs)—a class of cancer immunotherapy drugs. The findings may help unlock the full potential of TcEs and ...

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of ...

Glial cells play an important role in supporting the body's nervous system. Several types of glial cells exist. Learn more here.